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Affiliation(s)

1. Department of Sensory Signaling, Bogomoletz Institute of Physiology National Academy of Sciences of Ukraine, Kyiv 401601, Ukraine
2. Menora-Solel Bone LTD, A-Mada st.6, Yokneam, 2066721, Israel

ABSTRACT

Here we present a unique life path of Sergiy Gulyar, a world-known Ukrainian scientist who was overcoming extreme conditions studying them on himself. He has developed his determination and responsibility from his basic experiences as a surgeon and his desire to win from his involvement in sports. His research in underwater laboratories has shown a capacity to find untrodden pathways to understand and explain what others did not even suspect. His physiological studies on the role of sea depths, breathing mixtures, underwater exposures, and diving schemes marked the path to the aquanauts and undersea man. Studies of hyper depths equivalent to 2,500 m revealed the physiological limits of human being and demonstrated how to handle respiratory failure. Prof. S. Gulyar suggested a usage of natural physiological mechanisms to accelerate the re-adaptation process as a part of the high-mountain rehabilitation of hyperbaria-adapted people. Dissertations were defended, books and articles were written, a scientific school of followers was created. Unfortunately, during the Soviet period, Prof. S. Gulyar faced a set of organizational problems and obstacles from the Soviet regime. In particular, his works were classified or hushed up, his intellectual property was often used without mentioning the author and his scientific team was intimidated by criminal investigations. Main recognition during this period had come from professional societies in Europe and the United States. After the collapse of the Union of Soviet Socialist Republics (USSR), Prof. S. Gulyar introduced a number of innovations and inventions in electromagnetic medicine and physiology. In particular, he has managed to account for main common features of physiological effects of light stimulation produced by Lasers, Light-Emitted Diodes and Bioptron light sources. By doing so, some mystical dogmas were filtered out and new paths to sensible light-induced treatments were developed. At the same time, Prof. S. Gulyar has preserved the legacy of many generations of medical professionals who used light in their treatments. He has shown in his physiological experiments that stimulation of biologically active zones including acupuncture points light stimulation has a wide spectrum of biological effects including alleviation of pain symptoms. Now mono- and polychromatic visual and transcutaneous light therapy of pain has been recognized scientifically and clinically, and its place in medicine has been firmly established. Prof. S. Gulyar described a new functional system of the organism that regulates the electromagnetic equilibrium. A step into the future was the first experimentally grounded technology for the use of fullerene-modified light. Positive changes have been proven with its percutaneous and ocular use. These first results have yet to be fully analyzed, so a full investigation will be needed. Prof. S. Gulyar has published 20 monographs, 470 papers and abstracts, and received 11 patents. Many of his inventions have been implemented, the others are still awaiting implementation. This essay is based on the data obtained by the authors during many years of their personal cooperation starting from the Laboratory Ichthyander to the present day at the Bogomoletz Institute of Physiology of the National Academy of Sciences of Ukraine, as well as from the memoirs of Prof. S. Gulyar and the materials he provided.

KEYWORDS

Underwater medicine, compressed air works, Ichthyander and Chernomor underwater laboratories, pressure chambers, hyperbaria, nitrox, heliox, neonox, decompression, oxygen balance, adaptation, saturation diving, general high-pressure syndrome, Bioptron, Medolight, polarized light therapy, fullerene, historical modeling, ancient Slavic boat, underwater archeology, Bogomoletz Institute of Physiology of NASU, Zepter International Company.

Cite this paper

Journal of US-China Medical Science 19 (2022) 46-66

References

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[31]    Gulyar, S. A. 1980. “Interrelations of Respiration Circulation and Oxygen Regimes of Man under Hyperbaric Hyperoxy at 2.5-4 kgf/cm2.” Fiziol. J. 26 (1): 45-52. (in Russian)

[32]    Gulyar, S. A. 1980. “Dynamics of Respiration, Blood Circulation and Oxygen Regimes of Human Organism under Influence of Breathing Mixture Increased Density and Hyperoxia.” Fiziol. J. 26 (6): 823-9. (in Russian)

[33]    Gulyar, S. A., and Kolchinskaya, A. Z. 1982. Human Organism Oxygen Regimes during Staying in Nitrogen-Helium-Oxygen Medium under a Pressure of 11 kgf/cm2.” In Physiological Action of Hyperbaria. Kyiv: Ndumka, pp. 79-84. (in Russian)

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[36]    Gulyar, S. A., Ilyin, V. N., Dmitruk, A. I., and Moiseenko, E. V. 1990. “Physiological Mechanisms of Adaptation on Divers to the Conditions of Deep-Water Dives in the Arctic.” In EUBS 1990: Proc. Joint Meeting on Diving and Hyperbaric Med., Amsterdam, pp. 311-8.

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[39]    Gulyar, S. A., Olszanski, R., and Skrzynski, S. 2011. “Biophysical Method of Correction Disorders Caused by Hyperbaria. In Proceedings of the 37th Annual Meeting of the European Underwater and Baromedical Society, 24-27 August, 2011, Gdansk, p. 85.

[40]    Gulyar, S. A., Ilyin, V. N., Dmitruk, A. I., Zakharchenko, V. V., Evtushenko, A. L., and Beresetskaya, N. M. 1990. “Automatized System of Calculation of Divers Individual Regimes of Work and Rest at Depths 40-300 m in Heliox Saturation Dives.” In Proceedings Internat. Conf. on Ocean Res. and Underwater Technology Interoceano technology ‘90, Szczecin, pp. 141-53

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[42]    Gulyar, S. A., Ilyin, V. N., and Boltychev, I. R. 1990. “New in the Mechanics of Forced Human Respiration in an Extremely High Density Gas Environment.” Proc. of the USSR Academy of Sciences 315 (3): 751-4. (in Russian)

[43]    Gulyar, S. A., Ilyin, V. N., and Boltychev, I. R. 1991. “High Density Breathing Syndrome: I. Oscillations on Flow-Volume Curves during Forced Breathing in Dense Gas Medium.” Fiziol. J. 37 (4): 19-26. (in Russian)

[44]    Boltychev, I. R., Ilyin, V. N., and Gulyar, S. A. 1991.High Density Breathing Syndrome: II. Mechanics of Forced Breathing with Artificial Resistive Load in Normobaria.” Fiziol. J. 37 (4): 26-32. (in Russian)

[45]    Ilyin, V. N., Gulyar, S. A., and Boltychev, I. R. 1991.High Density Breathing Syndrome: III. Functional Value of Respiratory Flow Oscillations while Breathing in Dense Gas Medium.” Fiziol. J. 37 (4): 32-9. (in Russian)

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[47]    Gulyar, S. A. 1991. “Regulation and Correction of Oxygen Balance of Organism of Man at Hyperbaria.” In Proc. of the XVII Ann. Meet. of EUBS on Diving and Hyperbaric Med., Heraclion, Crete, Sept. 29-Oct. 3, 1991, pp. 105-12.

[48]    Gulyar, S. A., and Ilyin, V. N. 1993. “Restitution of Lung Ventilatory Function of Deep Divers in Mountains.” In Proc. of the XIX Ann. Meet. of EUBS on Diving and Hyperbaric Med. Trondheim, Norway, Aug. 17-20, 1993, pp. 89-92.

[49]    Olszanski, R., Gulyar, S. A., Klos, R., and Skrzynski, S. 1993. “Plateletal HaemostasisHyperbaric Air Exposures.” In Proc. of the XIX Ann.Meet.of EUBS on Diving and Hyperbaric Med. Trondheim, Norway, Aug. 17-20, 1993, pp. 163-8.

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[51]    Ilyin, V. N., Gulyar, S. A., Skrzynski, S., and Pachut, M. 1994. “Pulmonary Mechanical Function after Short-Term Dives to Depths down to 100 m.” In Proc. XX Ann. Meet. of EUBS on Diving and Hyperbaric Med., Istanbul, Turkey, Sept. 4-8, 1994, pp. 473-8.

[52]    Gulyar, S. A., Ilyin, V. N., Skrzynski, S., and Pachut, M. 1996. “Technology of Divers Workability Support: Decompression Enterosorbentive Detoxication.” In Proc. Internat. Joint Meeting on Hyperbaric and Underwater Med., Milano, Italy, Sept. 4-8, 1996, pp. 447-50.

[53]    Ilyin, V. N., Gulyar, S. A., and Olszanski, R. 1996. “Autonomic Nervous Function and Disorders of Circulation in Compressed Air.” In Proc. Internat. Joint Meeting on Hyperbaric and Underwater Med., Milano, Italy, Sept. 4-8, 1996, pp. 549-51.

[54]    Gulyar, S. A., Beloshitsky, P. V., Fedorchenko, V. I., Moiseenko, E. V., Litvinsky, A. M., Todosiev, V. P., Kramarenko, V. A., Ivanova, L. I., and Bilyk, I. I. 1985. “Influence of High Mountain Conditions on the Functional State of the Organism of Aquanauts, Trained for High Pressure and the Water Environment.” In Adaptation and Resistance of the Organism in the Mountains. Kyiv: Ndumka, pp. 138-55. (in Russian)

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[57]    Gulyar, S. A., Dmitruk, A. I., Ilyin, V. N., and Kramar, I. P. 1999. “On the Assessment of Age Limits for the Activity of Deep Divers.” Military Medical J. 320 (9): 66-8. (in Russian)

[58]    Gulyar, S. A. 2002. “Group and Individual Psychological Status of Winterers in Sociological Aspect. 1. The Problem of Antarctic Wintering and the Initial State.” Bull. Ukr. Ant. Center 4: 130-7. (in Russian)

[59]    Gulyar, S. A. 2006. “Harmony or Conflict.” Expedition 3 (1): 82-90. (in Russian)

[60]    Gulyar, S. A., Olszanski, R., and Cobos, S. 2009. “Psychological Peculiarities of a Year Stay in Antarctida: 1. Estimation of Selection and Inner Team Structure.” Polish Hyperbaric Research 29 (4): 37-48. (in Russian)

[61]    Gulyar, S. A., and Ilyin, V. N. 1998. “First Experience and Prospects of Antarctic Underwater Research.” Bull. Ukr. Ant. Center. 2: 214-27. (in Russian)

[62]    Gulyar, S. A. 2002. “Underwater Search in the Vicinity of the Antarctic Station Akademik Vernadsky. Diving 1: 35-9. (in Russian)

[63]    Limansky, Y. P., Tamarova, Z. A., Gulyar, S. A., and Bidkov, E. G. 2000. “Examination of the Analgetic Action of Polarized Light on the Acupuncture Point.” Fiziol. J. 46 (6): 105-11. (in Ukrainian)

[64]    Limansky, Y. P., Tamarova, Z. A., and Gulyar, S. A. 2003. “Suppression of Visceral Pain by Action of the Low Intensity Polarized Light on Antinociceptive Acupuncture Points.” Fiziol. J. 49 (5): 43-51. (in Ukrainian)

[65]    Gulyar, S. A. 2003. Medical Technologies Presentation. Kyiv: Zepter: 1-136. (in Russian)

[66]    Limansky, Y. P., Tamarova, Z. A., and Gulyar, S. A. 2006. “Suppression of Pain by Exposure of Acupuncture Points to Polarized Light.” Pain Res. Manag. 11 (1): 49-57.

[67]    Limansky, Y. P., Gulyar, S. A., and Samosyuk, I. Z. 2007. “Scientific basis of acupuncture.” Reflexotherapy 20 (2): 9-18. (in Russian)

[68]     Limansky, Y. P., Gulyar, S. A., and Samosyuk, I. Z. 2007. “Scientific Basis of Acupuncture: 2.” Kontakt. 9 (2): 391-402.

[69]    Limansky, Y. P., Gulyar, S. A., and Tamarova, Z. A. 2009. “Bioptron-Induced Analgesia: 2. Comparative Estimation of Antinociceptive Action of Polarized and Unpolarized Light.” In Anthology of Light Therapy. Kyiv: Bogomoletz Institute of Physiology of NASU, pp. 190-203. (in Russian)

[70]    Limansky, Y. P., Gulyar, S. A., and Tamarova, Z. A. 2009. “Bioptron-Induced Analgesia: 6. Effect of PILER-Light on Acute Short-Lasting Pain.” In Anthology of Light Therapy. Kyiv: Bogomoletz Institute of Physiology of NASU, pp. 225-34. (in Russian)

[71]    Tamarova, Z. A., Limansky, Y. P., and Gulyar, S. A. 2009. “Effect of Low-Intensity Red Polarized Light on Stress-Induced Behavior in Mice.” In Proc. VI Int. Symp. “Actual Problems of Biophysical Medicine”, May 14-17, 2009, Kyiv, pp. 104-5. (in Russian)

[72]    Gulyar, S. A., Tamarova, Z. A., and Taranov, V. V. 2022. “Innovative Light Therapy: 5. Anti-stress Effects of Polarized Polychromatic and Monochromatic Light of Halogen and LED Origin.” J. of US-China Medical Science 19 (2): 29-45.

[73]    Gulyar, S. A., and Tamarova, Z. A. 2019. “Comparison of the Analgetic Effect of Low-Intensive Polarized Polychromatic Light and Analgesics.” J. of US-China Medical Science 16 (1): 1-15.

[74]    Gulyar, S. A., Limansky, Y. P., and Tamarova, Z. A. 2007. Pain Color Therapy: Treatment of Pain Syndromes with Color Polarized Light (Manual). Kyiv: Bogomolets institute of physiology of NASU, pp. 1-128. (in Russian)

[75]    Limansky, Y. P., Gulyar, S. A., and Tamarova, Z. A. 2009. “Bioptron-Analgesia: 13. Comparative Evaluation of Efficacy of Analgesic Action of Red Polarized and Unpolarized Light for Animals with Tonic and Acute Pain.” In Anthology of Light Therapy. Kyiv: Bogomoletz Institute of Physiology of NASU, pp. 732-41. (in Russian)

[76]    Tamarova, Z. A., Limansky, Y. P., and Gulyar, S. A. 2009. “Antinociceptive Effects of Color Polarized Light in Animal Formalin Test Model.” Fiziol. J. 55 (3): 81-93. (in Russian)

[77]    Gulyar, S. A., and Tamarova, Z. A. 2020. “Analgesic Effects of Constant and Frequency-Modulated LED-Generated Red Polarized Light.” Neurophysiology 52 (4): 267-78.

[78]    Gulyar, S. A., and Tamarova, Z. A. 2021. “Innovative Light Therapy: 4. Influence of Polarization and Wavelength Range of Light on the Effectiveness of its Pain Relief Action.” J. of US-China Medical Science 18 (1): 1-19.

[79]    Cheng, K., Martin, L. F., Slepian, M. J., Amol, M., Patwardhan, A. M., and Ibrahim, M. M. 2021. Mechanisms and Pathways of Pain Photobiomodulation: A Narrative Review. J Pain. 22 (7): 763-77.

[80]    Gulyar, S. A., and Limansky, Y. P. 2003. “Mechanisms of Primary Reception of Electromagnetic Waves of Optical Range.” Fiziol. J. 49 (2): 35-44. (in Ukrainian)

[81]    Gulyar, S. A. 2003.The Concept of Electromagnetic Balance of the Body and the Environment: The Role of Bioptron Light Therapy.” In Proc. New TechnologiesThe Way to the Future. Donetsk: South-East, pp. 108-20. (in Russian)

[82]    Gulyar, S. A. 2009. “Electromagnetic Ecology and Bioptron Light Therapy Concept: Solved and Non-solved Questions.” In Anthology of Light Therapy. Kyiv: Bogomoletz Institute of Physiology of NASU, pp. 68-92. (in Russian)

[83]    Gulyar, S. A. 2018. “Accents of the Human Organism Electromagnetic Balance Regulation System.” Photobiol. and Photomed. 24: 52-68.

[84]    Voronenko, Y. V., Kusnetsova, L. V., Pukhlyk, B. M., and Gulyar, S. A. 2008. Allergology (Manual). Kyiv, pp. 1-366. (in Russian)

[85]    Kuznetsova, L. V., Babadzhan, V. D., Frolov, V. M., and Gulyar, S. А. 2012. Clinical and Laboratory Immunology. National Manual. Kyiv: Polygraph Plus, pp. 1-922. (in Ukrainian)

[86]    Gulyar, S. A., Moiseenko, E. V., Sirota, S. S., Grinevch, V. A., and Skudin, V. K. 1979. “Effect of People Stay in Nitrogen-Oxygen Environment at 5-12 kgf/cm2 on Certain Indices of Human Higher Nervous Activity.” Fiziol. J. 25 (5): 576-84. (in Russian)

[87]    Gulyar, S. A. 1981. Mental Performance of a Aquanauts in a Nitrogen-Oxygen Environment under Hyperbaria.” In Organization and Adaptation on Brain Functions. Proc. of the School of Young Scientists, Sept. 22-28, 1980, Varna-Sofia, pp. 144-64. (in Russian)

[88]    Gulyar, S. A. 2002. “Psychomedical, Bioelectromagnetic and Ecological Aspects of Antarctic Deprivation Problem. Bull. Ukr. Ant. Center 4: 231-4. (in Russian)

[89]    Gulyar, S. A., and Rudenko, I. V. 2002. Method of Generating Signal of Influence on Biological Object and Neutralization of Pathogenic Radiation and Device for Its Implementation. Declaration patent of Ukraine for the invention No. 49253 A issued 16.09.2002, Bull. 9. (in Ukrainian)

[90]    Korchin, I. A., and Gulyar, S. A. 2004. Light Therapy Device on Polarized Radiation. Patent of Ukraine for the invention No. 68039 A issued 15.07.2004, Bull. 7: 4, 96. (in Ukrainian)

[91]    Korchin, I. A., and Gulyar, S. A. 2008. The Device of Reflexotherapy Puncture by Polarized Light. Patent of Ukraine for a utility model No. 33577 issued on 25.06.2008, Bull. 12. (in Ukrainian)

[92]    Gulyar, S. A., and Taranov, V. V. 2019. Therapeutic Irradiation Device. Int. and European Pat. App. PCT/EP2019/079653. Internat Publ WO 2021/083507 A1. Applicant: Fieldpoint (Cyprus) Limited. Filled 30.09.2019, published 16.05.2021.

[93]    Gulyar, S. A., Limansky, Y. P., and Tamarova, Z. A. 2000. Pain and Bioptron: Treatment of Pain Syndromes by Polarized Light. Kyiv: Zepter, pp. 1-80. (in Russian)

[94]    Gulyar, S. A., Limansky, Y. P., and Tamarova, Z. A. 2004. Pain and Color (Manual). Kyiv-Donetsk: Biosvet, pp. 1-122. (in Russian)

[95]    Gulyar, S. A., and Kosakovskyi, A. L., eds. 2006, 2011. Bioptron-PILER-Light Application in Medicine (1st, 2nd ed.) Kyiv: Bogomoletz Institute of Physiology of NASU, pp. 1-152, 1-256. (in Ukrainian and Russian)

[96]    Gulyar, S. A., and Limansky, Y. P. 2006. Static Magnetic Fields and Their Application in Medicine. Kyiv: Bogomoletz Institute of Physiology of NASU, pp. 1-320. (in Russian)

[97]    Gulyar, S. A. 2009. Anthology of Light Therapy. Medical BIOPTRON Technologies. Kyiv: Bogomoletz Institute of Physiology of NASU, pp. 1-1024. (in Ukrainian and Russian)

[98]    Gulyar, S. A. 2021. Medolight: Basic Healing Effects of LED Device (5th ed.). Kyiv: IMIC, pp. 1-64.

[99]    Sushko, B. S., Limansky, Y. P., and Gulyar, S. A. 2007. “Action of the Red and Infrared Electromagnetic Waves of Light-Emitting Diodes on the Behavioral Manifestation of Somatic Pain.” Fiziol. J. 53 (3): 51-60. (In Ukrainian)

[100]  Gulyar, S. A., and Tamarova, Z. A. 2017. “Analgesic Effects of the Polarized Red+Infrared LED Light.” J of US-China Medical Science 14 (2): 47-57.

[101]  Gulyar, S. A., and Tamarova, Z. A. 2017. “Analgesic and Sedative Effects of Blue LED Light in Combination with Infrared LED Irradiation.” J of US-China Medical Science 14 (4): 143-56.

[102]  Koruga, D. 2016. Nanophotonic Filter Based on C60 for Hyperpolarized Light. Int. and European Pat. App. PCT/EP2016/063174. Applicant: Field point, Zepter Group filed June 09, 2016 and issued October 28, 2016.

[103]  Koruga, D. 2017. Hyperpolarized Light: Fundamentals of Nano Medical Photonics. Belgrade: Zepter World Book, pp. 1-306. (in English and in Serbian)

[104]  Gulyar, S. A., and Tamarova, Z. A. 2017. “Modification of Polychromatic Linear Polarized Light by Nanophotonic Fullerene and Graphene Filter Creates a New Therapeutic Opportunities.” J. of US-China Medical Science 14 (5): 173-91.

[105]  Gulyar, S. A., and Tamarova, Z. A. 2018. “Influence of Many-Month Exposure to Light with Shifted Wave Range and Partial Fullerene Hyperpolarization on the State of Elderly Mice.” J. of US-China Medical Science 15 (1): 16-25.

[106]  Gulyar, S. A., Filimonova, N. B., Makarchuk, M. Y., and Kryvdiuk, Y. N. 2019. “Ocular Influence of Nano-Modified Fullerene Light: 1. Activity of Default Networks of the Human Brain.J. of US-China Medical Science 16 (2): 45-54.

[107]  Gulyar, S. A., Filimonova, N. B., Makarchuk, M. Y., Krivdiuk, Y. N. 2019. “Ocular Influence of Nano-Modified Fullerene Light: 2. Time Correlation of the Choice and Simple Sensorimotor Reactions That Determine Blinding Compensation of the Driver. J. of US-China Medical Science 16 (3): 105-15.

[108]  Gulyar, S. A., Tamarova, Z. A., and Kirilenko, Y. K. 2019. “Ocular Influence of Nano-Modified Fullerene Light: 3. Speed and Quality of Visual Information Processing in Man.” J. of US-China Medical Science 16 (3): 116-33.

[109]  Gulyar, S. A., and Tamarova, Z. A. 2020. “Innovative Light Therapy: 1. Biological Effectiveness of Polychromatic Polarized Light Transmitted through Interference, Absorption and Fullerene Filters.” J. of US-China Medical Science 17 (1): 27-36.

[110]  Gulyar, S. A., and Tamarova, Z. A. 2020. “Innovative Light Therapy: 2. Determination of the Biological Contribution of Fullerene, as a Converter of Polarized Light, on a Model of Formalin-Induced Pain.” J. of US-China Medical Science 17 (2): 41-59.

[111]  Gulyar, S. A., and Tamarova, Z. A. 2020. “Peculiarities of the Fullerene-Halogen Light Influence on Inflammatory Pain, Depending on Characteristics of the Light Flux.” Medical Informatics and Engineering 2: 28-49. (in Russian)

[112]  Gulyar, S. A. 2001. “Ways of Peace and Harmony on the BoatPrincess Olga.Skipper 1: 55-8. (in Russian)

[113]  Gulyar, S. A. 2002 “Cossack Ways or Expedition Bohun. Native Nature 3: 30-4. (in Russian)

[114]  Gulyar, S. A., and Voronov, S. A. 2003. “Along the Great Silk Road on the Svarog Boat.” Skipper 6: 50-3. (in Russian)

[115]  Gulyar, S. Krugov, V., and Khmarov, V. 2003. Photo Chronicle of Travels in Time and Space. Kherson: Nadnipryanochka, pp. 1-12. (in Russian)

[116]  Gulyar, S. A., Voronov, S. A., Olszanski, R., Siryk, O. A., and Bogush, D. A. 2006. “Influence of Long Insolation during River and Sea Travelling on Open Boats.” Actual Problems of Transport Medicine 3 (1): 85-91. (in Russian)

[117]  Gulyar, S. A., Voronov, S. A., Olszanski, R., Siryk, O. A., and Bogush, D. A. 2009. “The Role of Many Days Influence of Sun Radiation High Doses on Human Organism during River and Sea Traveling on Open Ancient Boats.” In Anthology of Light Therapy. Kyiv: Bogomoletz Institute of Physiology of NASU, pp. 414-20. (in Russian)

[118]  Gulyar, S. A. 2006. “Underwater Traces of Sea Tragedies.All-Ukrainian Magazine about Metal 9 (3-4): 90-4. (in Russian)

[119]  Gulyar, S. A. 2008. “Lost World in the Depths of the Sea.” All about Metal 1: 60-3. (in Russian)

[120]  Gulyar, S. A. 2020. “Innovative Light Therapy: 3. Correction of the Acute Viral Respiratory Diseases Using Biophysical Capabilities of Bioptron-PILER-Light (Review).Journal of US-China Medical Science 17 (6): 219-49.

[121]  www.gulyar.org. (in English, Ukrainian and Russian)


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