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Affiliation(s)

Federal Institute of Sergipe, Aracaju, Brazil; University of Cruz Alta (UNICRUZ), Brazil; Federal University of Sergipe, Sao Cristovao, SE, Brazil

ABSTRACT

This study carries out an analysis of technological prospecting in biotechnology applied to human health, with an emphasis on gene and cell therapies. The aim is to identify the main technological innovations, the main investors and the most developed regions in the sector. Using the ORBIT Intelligence database, the 25 most cited patents (minimum of 10 citations) were analyzed. The abstracts of the patents were analyzed using IRAMUTEQ software, allowing thematic and technological patterns to be identified. The results show a concentration of investments in advanced therapies, highlighting the growing relevance of these technologies for the pharmaceutical industry and clinical research. The conclusion is that biotechnology for human health is on a growth path, with a direct impact on therapeutic innovation and the development of new medical approaches.

KEYWORDS

 biotechnology, technology prospecting, gene therapy, cell therapy, patents

Cite this paper

Elber Ribeiro Gama, Rodrigo de Rosso Krug, Robelius De-Bortoli. (2025). Technological Prospecting in Gene and Cell Therapies: A Global Analysis of Patents and Innovation in Human Health. US-China Education Review A, April 2025, Vol. 15, No. 4, 297-314.

References

Abusalah, M. A. H., Abd Rahman, E. N. S. E., & Choudhary, O. P. (2024). Evolving trends in stem cell therapy: An emerging and promising approach against various diseases. International Journal of Surgery, 110(11), 6862-6868.

Amaral, C. S. T., et al. (2020). New paths of biotechnology: Industry 4.0 innovations in human health. Revista Brasileira Multidisciplinar, 23(3), 203-231.

Anyanwu, E. C., et al. (2024). The role of biotechnology in healthcare: A review of global trends. World Journal of Advanced Research and Reviews, 21(1), 2740-2752.

Ari Yuka, S., et al. (2023). Recent advances in health biotechnology during pandemic. Sigma Journal of Engineering and Natural Sciences, 41(3).

Arif, A., et al. (2024). Global patent landscape in CRISPR-Cas. In CRISPRized Horticulture Crops (pp. 487-506). Academic Press.

Azizan, A., Ahmed, W., & Razak, A. H. A. (2024). Sensing health: A bibliometric analysis of wearable sensors in healthcare. Health and Technology, 14(1), 15-34.

Bhatia, D., Paul, S., Acharjee, T., & Ramachairy, S. S. (2024). Biosensors and their widespread impact on human health. Sensors International, 5, 100257.

Bikard, M., Vakili, K., & Teodoridis, F. (2019). When collaboration bridges institutions: The impact of university-industry collaboration on academic productivity. Organization Science, 30(2), 426-445.

Brandão Neto, N., Faria, L. D. A., & Melo, F. C. L. D. (2024). Identifying technological trends and promoting strategies to boost innovation and technology transfer: A case study on the patent portfolio of Brazilian public research institutions. Journal of Aerospace Technology and Management, 16, e1624.

Charlier, J., et al. (2024). From discovery to innovation in animal health: Maturing emerging technologies for industrial development. Biologicals, 87, 101783.

Chaudhary, P., et al. (2023). Oxidative stress, free radicals and antioxidants: Potential crosstalk in the pathophysiology of human diseases. Frontiers in Chemistry, 11, 1158198.

Cox, D. B. T., et al. (2017). RNA editing with CRISPR-Cas13. Science, 358(6366), 1019-1027.

Da Silva, R. G. L. (2024). The advancement of artificial intelligence in biomedical research and health innovation: Challenges and opportunities in emerging economies. Globalization and Health, 20(1), 44.

De Lima Júnior, P. G. (2024). Conceptions of hermeneutic bioethics. Global Crossings, 1(1), 393-416.

Dos Santos Fonseca, L. M., et al. (2024). An overview on recent patents and technologies on nanoparticles for nucleic acid delivery. Expert Opinion on Therapeutic Patents, 34(3), 171-186.

Dunbar, C. E., et al. (2018). Gene therapy comes of age. Science, 359(6372), eaan4672.

Esfandyarpour, A., et al. (2024). From depth and breadth of knowledge to technological capability: A journey inside a firm’s intellectual capital. R&D Management.

Figueiredo, P. N. (2023). National innovation strategy: A brief contribution to its effectiveness from the perspective of technological capacity accumulation. Revista de Administração Pública, 57(5), e2022-0418.

Gartland, K. M. A., & Gartland, J. S. (2018). Opportunities in biotechnology. Journal of Biotechnology, 282, 38-45.

Giansanti, D. (2024). Joint expedition: Exploring telehealth and the digital healthcare landscape as a team integration. In Healthcare (p. 585). MDPI.

Hrebeniuk, V., et al. (2024). Institutional aspects of rivalry for technological leadership: Market versus security. In The AI revolution: Driving business innovation and research: Volume 1 (pp. 39-53). Springer Nature Switzerland.

Hrebennyk, N., et al. (2024). Reviewing the development of science parks and their impact on the economy in the context of globalization. Access Journal, 5(3), 526-550.

Jeon, E., Yoon, N., & Sohn, S. Y. (2023). Exploring new digital therapeutics technologies for psychiatric disorders using BERTopic and PatentSBERTa. Technological Forecasting and Social Change, 186, 122130.

Klein, C., et al. (2024). The present and future of bispecific antibodies for cancer therapy. Nature Reviews Drug Discovery, 23(4), 301-319.

Kliegman, M., et al. (2024). A roadmap for affordable genetic medicines. Nature, 1-8.

Lee, H. L., & Vavitsas, K. (2021). Driving innovation in biotechnology with private-public partnerships: A Singapore perspective. Biotechnology Notes, 2, 59-62.

Liao, C., Xiao, S., & Wang, X. (2023). Bench-to-bedside: Translational development landscape of biotechnology in healthcare. Health Sciences Review, 7, 100097.

Liu, T., Yang, X., & Zheng, Y. (2020). Understanding the evolution of public-private partnerships in Chinese e-government: Four stages of development. Asia Pacific Journal of Public Administration, 42(4), 222-247.

Peter, C., Cajka, A., & Krpalek, P. (2023). The role of universities as the institutional drivers of innovation at the regional level. Terra Economicus, 21(1), 94-107.

Prajapati, R. N., et al. (2024). Recent advances in pharmaceutical design: Unleashing the potential of novel therapeutics. Current Pharmaceutical Biotechnology, 25(16), 2060-2077.

Taherdoost, H. (2024). The role of R&D in business. In Innovation through research and development: Strategies for success (pp. 23-46). Springer Nature Switzerland.

Tseng, F. C., Huang, M. H., & Chen, D. Z. (2020). Factors of university-industry collaboration affecting university innovation performance. The Journal of Technology Transfer, 45, 560-577.

Van Den Bos, C., et al. (2024). Manufacturing and quality of advanced therapeutics: Cellular therapies, CAR-T and gene therapies. In Biopharmaceutical manufacturing: Progress, trends and challenges (pp. 453-488). Springer International Publishing.

Wang, H., et al. (2024). Addressing healthy aging in China: Practices and perspectives. BioScience Trends, 18(3), 212-218.

Zhang, F. (2019). Development of CRISPR-Cas systems for genome editing and beyond. Quarterly Reviews of Biophysics, 52, e6.

Zhou, Y., & Sun, F. (2022). Creating knowledge assets under biocapitalism: Analyzing China’s biomedical industry and its patent networks. Economic Geography, 98(5), 411-437.

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