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ABSTRACT

Hyperpigmentation can be caused by long-term UV (ultraviolet) exposure, hormonal imbalances, skin ageing processes, as well as skin inflammation, skin injuries and accumulation of hemosiderin. A brightening complex consisting of niacin, Rumex spp. and biomimetic peptide is supposed to be an efficient alternative for commonly used brightening agents. In-vivo research of night cream (1474) was conducted in order to confirm the safety and efficiency of tri-active brightening cream in treatment of facial skin hyperpigmentation. The research was conducted on a group of 30 female patients, and the night cream was applied once a day for six weeks. The research was done by the use of VISIA® system, multifunctional MPA and PRIMOS® projection system, which was applied with VISIOSCAN camera. Besides, the research also included a questionnaire. A decrease in melanin by 16% and 25% at 93% and 96% of patients, respectively, was observed after three and six weeks of regular application of the cream. Furthermore, we also noticed reduction of erythema which was accompanied by an increase in the skin moisture. Brightening of changes on hyperpigmented facial skin proved to be efficient after an application of tri-active complex which was a component of the night cream.

KEYWORDS

Hyperpigmentation, brightening, tri-active complex. 

Cite this paper

Zasada, M., et al. 2016. “Efficacy of Tri-active Brightening and Anti-aging Complex in Treatment of Facial Skin Hyperpigmentation.” Journal of Pharmacy and Pharmacology 4 (10): 564-573.

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