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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Article
Author(s)
Sri Hartati1, Tri Untari2, Ida Fitriyani3 and Bambang Sutrisno4
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DOI:10.17265/2161-6256/2015.08.008
Affiliation(s)
1. Department of Veterinary Clinical Science, Faculty of Veterinary Medicine, Gadjah Mada University, Yogyakarta 55281, Indonesia
2. Department of Microbiology, Faculty of Veterinary Medicine, Gadjah Mada University, Yogyakarta 55281, Indonesia
3. Department of Pharmacology, Faculty of Veterinary Medicine, Gadjah Mada University, Yogyakarta 55281, Indonesia
4. Department of Pathology, Faculty of Veterinary Medicine, Gadjah Mada University, Yogyakarta 55281, Indonesia
ABSTRACT
The aim of this research was to know the effect of herbal as
immunomodulator on chicken layer vaccinated with avian influenza. A total of 60
chickens were alloted into three treatment groups:
control group (KA), group KB and group KC, with 20 chicken each group. All the chickens were vaccinated with
Newcastle disease (ND) in the age of one week, and a week
later they were vaccinated with
avian influenza (AI). The chickens in group KB were drunken with
herbal solution containing of 5 g turmeric (Curcuma heyneana Val.) and 25 g phyllanthus (Phyllanthus niruri L.) and group KC were drunken with
herbal solution containing of 36 g the herbals formula
Viranur and 25 g phyllanthus (Phyllanthus niruri L.), respectively for four weeks. Thirty days
after AI vaccinated, all of chicken were
weighed and necropsied. Samples from bursa of Fabricius, tymus and spleen were
taken for weighing and histopathological examination. The weight indexs of
bursa of Fabricius, tymus and spleen were not significantly different between
control group and treatment group in the considered
statistically significance (P > 0.05), but the treatment groups (KB
and KC) had higher weight index. The
histopathologically changes of spleen in both control group and treatment groups were not
different, although in the group KC, in bursa of Fabricius, there was lymphocyte
increase in its lymphoid follicles; and in the group KB and KC, the tymus were more
widening in the cortex than medulla. The conclusion of this study showed that the herbals can
stimulate lymphocyte activity.
KEYWORDS
Herbal, immunomodulator, histopathologic, bursa of Fabricius, thymus, spleen, layer chicken, AI.
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