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ABSTRACT

The pharmaceutical market of Ukraine in January 2015 was registered 71 drug based acetylsalicylic acid (ASA), for which 52% combined. The most common combinations of ASA with acetaminophen and caffeine (45.9%), magnesium hydroxide (18.9%), bisoprolol (10.8%), ascorbic acid (8.1%), clopidogrel (5.4%). Comparing markets combined drugs ASA of Ukraine, the Russian Federation, 28 EU countries, Norway, Switzerland, India, Syria, Australia and the USA identified the active pharmaceutical ingredients, combined with ASA in a single dosage form. The analysis of questionnaires 40 pharmacists pharmacies Ternopil, Khmelnytsky and Kyiv regions of Ukraine noted that the biggest demand is mono-drugs ASA, Citramon, Askofen and Cardiomagnyl. Methods of pharmacoeconomic studies proved efficient use Upsaryn UPSA with vitamin C tabl. spike. tuba in box number 20 BMS (France), Citramon tablets number 6 PJSC “Monfarm” (Ukraine) and Cardiomagnyl tabl. film-coated shell 75 mg in bottle number 100 Nycomed Austria (Austria). On the basis of six State Forms of drugs in Ukraine (2009-2014) was found that the combination of drugs based on ASA is recommended to use of ascorbic acid (Aspiryn® C, Asprovit C, Upsarin UPSA with vitamin C), dipyridamole (Agrenox®), magnesium hydroxide (Cardiomagnyl, Cardiomagnyl Forte). Some of the standard combination of ASA (combination of paracetamol and caffeine) are not in form. For optimize State Form of drugs by improving health system in Ukraine can be useful pharmacoeconomic analysis of combination therapies with the current official system to note the combination of ASA with statins, esomeprazole, isosorbide.

KEYWORDS

Acetylsalicylic acid, combined drugs, supply and demand, pharmacoeconomic research, formular.

Cite this paper

Volodymyrivna, T. O., and Sergii'vna, V. L. 2015. “Trend Analysis of Combined Drugs Creation (for Example Acetylsalicylic Acid).” Journal of Pharmacy and Pharmacology 3 (10): 451-462.

References

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