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Synthesis of Nanostructured Erbium Oxides and Investigation of Influence Oxides on the Immune System and of Some Animal Tissues



Author(s)

Abdusalyamova Makhsuda, Rakhimov Ismatillo, KhaidarovKarim, Makhmudov Fakhod, Sadyrov Artur, Shaimardanov Ernest, AL-Abed Souhail R. and Shulga Yuri

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DOI:10.17265/1934-7375/2014.05.007

Nanostructured erbium oxides (Er₂O₃) with coherent scattering length 26, 31, 62 and 65 nm were obtained using as a precursor of erbium chloride and erbium oleate. The influences of Er₂O₃ on the immune system and some animal tissues were carried out. The experiments have been made on white mouse’s and outbred rats. Complex pharmaco-toxicological research presented erbium oxide nanostructure size of coherent scattering regions 26, 31, 56 and 65 nm showed that when administered orally no acute toxicity, no effect on the immune system of the body, has no effect on blood cells. But, long-term (30 day) intragastric administration shows toxicities on the internal organs of experimental animals, which lead to structural changes and functional impairment due to tissue accumulation of nanoparticles.

Nanostructured, erbium oxides, pharmaco-toxicological.