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Histopathological Characteristics of Atrophic Gastritis in Adult Population



Author(s)

Marija Milićević, Snežana Božanić and Nenad Šolajić

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DOI:10.17265/2328-2150/2015.03.004

Introduction: Chronic gastritis is inflammation of the gastric mucosa. It can be non-atrophic and atrophic. Atrophy is defined as the loss of appropriate glands. It is frequently located in antral mucosa as consequence of Helicobacter pylori infection and it is associated with intestinal gastric cancer. Goal: Describe histopathological and demographic characteristics of atrophic gastritis. Matherial and methods: We assessed the pathological reports of 100 patients with atrophic gastritis whose characteristics were evaluated by using a semiquantitative scale of Sidney system of classification of gastritis. To assess the significance between the incidence of various parametres we used χ² test. Results: We found that the difference in frequency of atrophic gastritis between men and women was not statistically significant. The difference in distribution is statistically significant in favor of the antrum. Among patients who have atrophy with Helicobacter pylori infection and intestinal metaplasia and those who do not have metaplasia, it was found that the difference is highly statistically significant. Conclusion: The most frequent localisation of atrophic gastritis is antral mucosa. There is no difference between men and women in frequency of atrophic gastritis, while the aging is related with more often occurrence of atrophic gastritis.

Gastritis, atrophic, metaplasia, Helicobacter pylori.

Milićević, M., et al. 2015. “Histopathological Characteristics of Atrophic Gastritis in Adult Population.” Journal of Pharmacy and Pharmacology 3 (3): 133-138.